TY - JOUR AU - Mariya Ali, AU - Tahira Naseem, AU - Farooq Abdul Hakim Bajwa, AU - Saira Zafar, AU - Asma Akram, AU - Hirra Ghaffar, PY - 2020/12/02 Y2 - 2024/03/29 TI - An Association of Vitamin D Insufficiency with Elevated Serum Uric Acid Levels Among Postmenopausal Women JF - Proceedings JA - Proceedings S.Z.M.C VL - 34 IS - 3 SE - Articles DO - 10.47489/p000s343z7601-6mc UR - https://proceedings-szmc.org.pk/index.php/szmc/article/view/22 SP - 41-45 AB - <p><strong>Introduction: </strong>Deficiency of vitamin D and raised levels of serum uric acid are considered independent risk factors for causing cardiovascular diseases.</p><p><strong>Aims &amp; </strong><strong>Objectives:</strong> This study was carried out to study Serum Uric acid and Vitamin D levels in postmeopausal women to find association of hypovitaminosis D with hyperuricemia.</p><p><strong>Place and duration of study:</strong> It was a cross-sectional analytical study. Postmenopausal women more than 55 years of age with BMI between 25-30 kg/m<sup>2</sup> were included in the study. The study was conducted at the Department of Biochemistry and Chemical Pathology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore over a period of six months.</p><p><strong>Material &amp; Methods:</strong> Eighty subjects were included in this study. They were divided into two groups i-e, normouricemic group and hyperuricemic group based onserum uric acid level.Vitamin D levels of both groups were then measured.</p><p><strong>Results:</strong> The hyperuricemic group had markedly lower vitamin Dlevels as compared to normouricemic group. Moreover, vitamin D had a negative correlation with uric acid in the hyperuricemic group i-e, higher the uric acid level, lower was vitamin D. Multiple regression analysis was also performed for studying the relation of vitamin D with uric acid levels in the two groups overall. It was observed that one mg/dl increase in uric acid caused an average decrease of 2.43 ng/ml in vitamin D.</p><p><strong>Conclusion:</strong> It may be concluded from this study that association of hypovitaminosis D with hyperuricemia in postmenopausal women can be used for planning an early intervention to prevent cardiovascular diseases in them.</p> ER -