Adverse Blood Transfusion Reaction in Tertiary Care Hospitals an Initiative Towards Improvement: A Multi Center Study

Authors

  • Shizra Kaleemi Department of Pathology, University College of Medicine and Dentistry, Lahore
  • Lubna Humayun Department of Pathology, University College of Medicine and Dentistry, Lahore
  • Hamna Salahuddin Department of Pathology, University College of Medicine and Dentistry, Lahore
  • Farah Arif Department of Pathology, Jinnah Hospital, Lahore
  • Asma Akhtar Department of Pathology, FMH College of Medicine & Dentistry, Lahore
  • Ayesha Nasir Department of Pathology, Jinnah Hospital, Lahore

Keywords:

Adverse transfusion reactions(ATRs), Hemo-vigilance, febrile non-hemolytic transfusion reactions, Allergic reactions

Abstract

Introduction: Blood and blood components transfusion is a life-saving procedure, but it carries the risk of adverse outcomes. Hemo-vigilance is a surveillance system that includes reporting and analysis of adverse events related to blood transfusion and taking steps to prevent their occurrence or recurrence

Aims & Objectives: This study is to determine the incidence and type of adverse transfusion reactions and type of blood products associated, in patients had undergone blood transfusion.

Place and duration of study: A retrospective descriptive cross-sectional study Blood bank, Pathology department, University College of Medicine / University of Lahore Teaching Hospital, Lahore and Blood bank, Mansoorah Teaching Hospital, Lahore. The study was conducted over a period of 04 years (1st January 2018 to 31st December 2021).

Material & Methods: All the adverse blood transfusion reactions reported to Blood Bank during the 4 years were

analyzed according to institution's protocol.

Results: Out of 9597 units transfused, 72 (0.75%) adverse transfusion reactions were reported. Febrile non hemolytic transfusion reactions (0.36%) were the most frequent type of reaction followed by Allergic reactions (0.33%). ATRs were mostly associated with whole blood followed by Pack Cell Volume (PCVs).

Conclusion: For an accurate estimation of ATR incidence, proper transfusion monitoring and reporting of all such responses will be required. To enhance the quality, safety, efficacy, and cost-effectiveness of blood and its components and as well as the donation process, an effective hemo-vigilance system must be established

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Published

2022-04-29

How to Cite

1.
Shizra Kaleemi, Lubna Humayun, Hamna Salahuddin, Farah Arif, Asma Akhtar, Ayesha Nasir. Adverse Blood Transfusion Reaction in Tertiary Care Hospitals an Initiative Towards Improvement: A Multi Center Study. Proceedings S.Z.M.C [Internet]. 2022Apr.29 [cited 2022May29];36(2):40-5. Available from: http://proceedings-szmc.org.pk/index.php/szmc/article/view/244