An Association of Vitamin D Insufficiency with Elevated Serum Uric Acid Levels Among Postmenopausal Women

Authors

  • Mariya Ali Department of Chemical Pathology, Continental Medical College, Lahore
  • Tahira Naseem Department of Biochemistry & Chemical Pathology, Shaikh Zayed Medical Complex, Lahore
  • Farooq Abdul Hakim Bajwa Department of Radiology, Lahore General Hospital, Lahore
  • Saira Zafar Department of Microbiology, Continental Medical College, Lahore
  • Asma Akram Department of Microbiology, Continental Medical College, Lahore
  • Hirra Ghaffar Department of Microbiology, Continental Medical College, Lahore

DOI:

https://doi.org/10.47489/p000s343z7601-6mc

Keywords:

Hyperuricemia, Hypovitaminosis D, Cardiovascular diseases

Abstract

Introduction: Deficiency of vitamin D and raised levels of serum uric acid are considered independent risk factors for causing cardiovascular diseases.

Aims & Objectives: This study was carried out to study Serum Uric acid and Vitamin D levels in postmeopausal women to find association of hypovitaminosis D with hyperuricemia.

Place and duration of study: It was a cross-sectional analytical study. Postmenopausal women more than 55 years of age with BMI between 25-30 kg/m2 were included in the study. The study was conducted at the Department of Biochemistry and Chemical Pathology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore over a period of six months.

Material & Methods: Eighty subjects were included in this study. They were divided into two groups i-e, normouricemic group and hyperuricemic group based onserum uric acid level.Vitamin D levels of both groups were then measured.

Results: The hyperuricemic group had markedly lower vitamin Dlevels as compared to normouricemic group. Moreover, vitamin D had a negative correlation with uric acid in the hyperuricemic group i-e, higher the uric acid level, lower was vitamin D. Multiple regression analysis was also performed for studying the relation of vitamin D with uric acid levels in the two groups overall. It was observed that one mg/dl increase in uric acid caused an average decrease of 2.43 ng/ml in vitamin D.

Conclusion: It may be concluded from this study that association of hypovitaminosis D with hyperuricemia in postmenopausal women can be used for planning an early intervention to prevent cardiovascular diseases in them.

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Published

2020-12-02

How to Cite

1.
Mariya Ali, Tahira Naseem, Farooq Abdul Hakim Bajwa, Saira Zafar, Asma Akram, Hirra Ghaffar. An Association of Vitamin D Insufficiency with Elevated Serum Uric Acid Levels Among Postmenopausal Women . Proceedings S.Z.M.C [Internet]. 2020 Dec. 2 [cited 2024 Jun. 15];34(3):41-5. Available from: https://proceedings-szmc.org.pk/index.php/szmc/article/view/22